The Thyroid Binding Globulin

This week I have again stood in amazement at the miracle of life. To be sure, each week I marvel at the wonder of life, but some weeks are different than others. This week has been a blur between running my life as a midwife and my life as a teacher. Most of this week, I have been more of a teacher than a midwife, but there was one baby too. I do hate boredom and weeks like this prove that fact.

For the past several years, I have developed and taught several different midwifery classes. This weekend, I attempted to capture them on film. After 2 days, and 8 hours of recorded sessions, my feet are killing me, but my heart is happy.

I enjoy teaching. I thrive on the “light bulb” moments. The times when I understand and grasp the concept, and the times when I notice this “light bulb” in those I am teaching.

Of the many concepts in my research for this week’s last class, a class on understanding the thyroid, one thing stands out greater than the others. It is the thyroid binding globulin.Before I started researching for the class, I couldn’t have told you what it was or even that it existed. But let me tell you why I marvel at this tiny strand of protein, The Thyroid Binding Globulin.

The Thyroid, a small endocrine organ, is located right below your voice box.The thyroid’s main purpose is to produce hormones that enable the body to convert the calories you take in, into valuable energy. However, these hormones can’t get where they need to go unless they are protected by something that will pick them up from the thyroid and take them to where they are needed. This job falls to the thyroid binding globulin.

Thyroid binding globulin is produced by the liver and made in such a way as to be able to bind with the thyroid hormone, take it where it needs to go, and drop it off only where it needs to be. Tiny, yet extremely complex, this globulin (measured in kilodaltons, a unit of measurement that is about 10 to the negative 27th power of a kilogram) has 394 amino acids in an exact and precise layout that allows it to do its very important job.

This astounds me. A tiny strand of protein, with complex layers, designed specifically to pick up only this hormone and drop this hormone off only where it’s needed.And while this astounds me, what really blows my socks off is that this globulin is present and functioning in baby that is only 12 weeks gestation.

Twelve weeks, just three short months to go from non-existent to a baby with a functioning thyroid and matching thyroid binding globulin. Not to mention the myriads of other functions occurring in this tiny life! My mind just cannot wrap around the intelligence of design required to create something so complex.

And so I stop to marvel again, and stand in awe of God, my Creator, who can not only plan out such a complex globulin, but who created it, and made it function in me, when I was yet unborn.

Truly, “It is the glory of God to conceal a matter;to search out a matter is the glory of kings.”